Comparison · Performance
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Compare up to 4 peptides from the Performance category. Tick any two or more — mechanism, protocols, side effects, stacking partners, and best $/mg update instantly.
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4 / 4 selected
- Fitness enthusiasts looking for cutting-edge muscle-building insights
- Bodybuilders curious about future muscle growth technologies
- Athletes interested in muscle mass research
- Aspiring endurance athletes looking for a performance edge
- Biohackers interested in cellular energy and muscle efficiency
- Fitness enthusiasts curious about cutting-edge research
- People exploring new weight loss strategies beyond diet and exercise.
- Biohackers interested in cutting-edge fat loss research.
- Fitness enthusiasts curious about novel approaches to managing body composition.
- Bodybuilders looking to maximize muscle growth
- Athletes aiming to gain strength and size
- Fitness enthusiasts interested in cutting-edge muscle science
- Researchers studying muscle-wasting conditions
- Anyone seeking FDA-approved muscle growth solutions
- Individuals uncomfortable with experimental therapies
- Those prioritizing safety-confirmed products
- Competitive athletes subject to drug testing
- Individuals seeking FDA-approved performance enhancers
- Those uncomfortable with experimental compounds
- Anyone looking for FDA-approved weight loss treatments.
- Individuals with existing kidney issues.
- Those averse to experimental and early-stage research treatments.
- Casual gym-goers who aren't into experimental science
- Individuals looking for FDA-approved supplements
- People concerned about untested long-term effects
- Myostatin and activin pathway blockade
- Lean mass increase in early human trials
- Explored in Duchenne muscular dystrophy
- AMPK activation & endurance phenotype (preclinical)
- Glucose uptake in skeletal muscle
- Mitochondrial biogenesis signaling
- Adipose vasculature ablation (preclinical)
- Weight loss in early human study
- Mechanism distinct from GLP-1 agonists
- Myostatin neutralization
- Hypertrophy in primate models
- Explored in muscular dystrophy research
ACE-031 is a recombinant fusion protein combining the extracellular domain of the activin receptor type IIB with an Fc region. Acting as a decoy receptor, it binds myostatin, activin, and related TGF…
AICAR is a small molecule (not a peptide) analog of AMP that, once phosphorylated intracellularly to ZMP, directly activates AMP-activated protein kinase (AMPK). Research shows AMPK activation stimul…
Adipotide is an experimental peptidomimetic that couples a homing motif targeting prohibitin on white adipose tissue vasculature to a pro-apoptotic sequence (KLAKLAK). In preclinical research, bindin…
Follistatin is a naturally occurring secreted glycoprotein that binds and neutralizes members of the TGF-β superfamily, most notably myostatin (GDF-8) and activin. By sequestering myostatin, research…
- Epistaxis (nosebleeds) — cited reason for clinical program discontinuation
- Telangiectasias (small dilated blood vessels)
- Injection-site reactions
- Hypotension and bradycardia at high doses
- Transient hyperuricemia
- GI upset and nausea
- Renal tubular dysfunction observed in Phase 1 human trial
- Dose-dependent nephrotoxicity in animal models
- Injection-site irritation
- Injection-site irritation
- Theoretical disruption of activin signaling affecting reproductive and pituitary function
- Potential for disproportionate muscle growth exceeding tendon capacity in animal models
- Active or suspected malignancy
- Bleeding disorders or anticoagulant therapy
- Pregnancy and lactation
- Cardiac arrhythmia or conduction disease
- Gout or hyperuricemia
- Pregnancy and lactation
- Renal impairment or history of kidney disease
- Dehydration
- Pregnancy and lactation
- Active or suspected malignancy (myostatin/activin pathways are implicated in tumor suppression in some tissues)
- Pregnancy and lactation
- Known cardiac hypertrophy or cardiomyopathy
Think of it as
Think of it as a muscle-building bouncer.Best for
- Fitness enthusiasts looking for cutting-edge muscle-building insights
- Bodybuilders curious about future muscle growth technologies
- Athletes interested in muscle mass research
Probably not for you if…
- Anyone seeking FDA-approved muscle growth solutions
- Individuals uncomfortable with experimental therapies
- Those prioritizing safety-confirmed products
Key benefits
- Myostatin and activin pathway blockade
- Lean mass increase in early human trials
- Explored in Duchenne muscular dystrophy
Mechanism of action
ACE-031 is a recombinant fusion protein combining the extracellular domain of the activin receptor type IIB with an Fc region. Acting as a decoy receptor, it binds myostatin, activin, and related TGF…
Typical protocol
Reported side effects
- Epistaxis (nosebleeds) — cited reason for clinical program discontinuation
- Telangiectasias (small dilated blood vessels)
- Injection-site reactions
Contraindications
- Active or suspected malignancy
- Bleeding disorders or anticoagulant therapy
- Pregnancy and lactation
Stacks well with
Best $/mg
Think of it as
Think of it as a secret endurance booster for your muscles.Best for
- Aspiring endurance athletes looking for a performance edge
- Biohackers interested in cellular energy and muscle efficiency
- Fitness enthusiasts curious about cutting-edge research
Probably not for you if…
- Competitive athletes subject to drug testing
- Individuals seeking FDA-approved performance enhancers
- Those uncomfortable with experimental compounds
Key benefits
- AMPK activation & endurance phenotype (preclinical)
- Glucose uptake in skeletal muscle
- Mitochondrial biogenesis signaling
Mechanism of action
AICAR is a small molecule (not a peptide) analog of AMP that, once phosphorylated intracellularly to ZMP, directly activates AMP-activated protein kinase (AMPK). Research shows AMPK activation stimul…
Typical protocol
Reported side effects
- Hypotension and bradycardia at high doses
- Transient hyperuricemia
- GI upset and nausea
Contraindications
- Cardiac arrhythmia or conduction disease
- Gout or hyperuricemia
- Pregnancy and lactation
Stacks well with
Best $/mg
Think of it as
Think of it as a targeted demolition crew for fat cells.Best for
- People exploring new weight loss strategies beyond diet and exercise.
- Biohackers interested in cutting-edge fat loss research.
- Fitness enthusiasts curious about novel approaches to managing body composition.
Probably not for you if…
- Anyone looking for FDA-approved weight loss treatments.
- Individuals with existing kidney issues.
- Those averse to experimental and early-stage research treatments.
Key benefits
- Adipose vasculature ablation (preclinical)
- Weight loss in early human study
- Mechanism distinct from GLP-1 agonists
Mechanism of action
Adipotide is an experimental peptidomimetic that couples a homing motif targeting prohibitin on white adipose tissue vasculature to a pro-apoptotic sequence (KLAKLAK). In preclinical research, bindin…
Typical protocol
Reported side effects
- Renal tubular dysfunction observed in Phase 1 human trial
- Dose-dependent nephrotoxicity in animal models
- Injection-site irritation
Contraindications
- Renal impairment or history of kidney disease
- Dehydration
- Pregnancy and lactation
Stacks well with
Best $/mg
Think of it as
Think of it as a muscle growth accelerator.Best for
- Bodybuilders looking to maximize muscle growth
- Athletes aiming to gain strength and size
- Fitness enthusiasts interested in cutting-edge muscle science
- Researchers studying muscle-wasting conditions
Probably not for you if…
- Casual gym-goers who aren't into experimental science
- Individuals looking for FDA-approved supplements
- People concerned about untested long-term effects
Key benefits
- Myostatin neutralization
- Hypertrophy in primate models
- Explored in muscular dystrophy research
Mechanism of action
Follistatin is a naturally occurring secreted glycoprotein that binds and neutralizes members of the TGF-β superfamily, most notably myostatin (GDF-8) and activin. By sequestering myostatin, research…
Typical protocol
Reported side effects
- Injection-site irritation
- Theoretical disruption of activin signaling affecting reproductive and pituitary function
- Potential for disproportionate muscle growth exceeding tendon capacity in animal models
Contraindications
- Active or suspected malignancy (myostatin/activin pathways are implicated in tumor suppression in some tissues)
- Pregnancy and lactation
- Known cardiac hypertrophy or cardiomyopathy
Best $/mg
For research purposes only. Not medical advice.