Comparison · GLP-1
SIDE BY SIDE
Compare up to 4 peptides from the GLP-1 category. Tick any two or more — mechanism, protocols, side effects, stacking partners, and best $/mg update instantly.
Pick up to 4
Tick any 2–4 peptides from this category. The comparison updates instantly.
4 / 4 selected
- Fitness enthusiasts looking to target stubborn fat areas
- People curious about alternatives to traditional HGH
- Those interested in managing weight with minimal side effects
- People looking to manage their weight more effectively.
- Those who struggle with feeling full after meals.
- Individuals interested in cutting-edge weight management options.
- Biohackers curious about new appetite-regulating peptides.
- People struggling with weight management who want to feel less hungry.
- Those managing type 2 diabetes looking for better blood sugar control.
- Individuals at risk of heart issues who need an additional protective measure.
- People looking to lose weight when other methods haven't worked.
- Those managing type 2 diabetes and seeking better blood sugar control.
- Individuals curious about cutting-edge metabolic health strategies.
- Individuals expecting dramatic weight loss results
- People looking for a growth hormone replacement
- Anyone wary of peptides without extensive human trial success
- Anyone uncomfortable with investigational compounds.
- People seeking a quick fix without lifestyle changes.
- Individuals who prefer tried-and-true methods over new research.
- Anyone uncomfortable with daily injections.
- People looking for an over-the-counter solution.
- Those who aren't managing weight or blood sugar issues.
- Anyone uncomfortable with investigational treatments or needles.
- Individuals not struggling with weight or metabolic health issues.
- Those looking for quick fixes without lifestyle changes.
- Lipolytic signaling (preclinical)
- Cartilage and joint research
- Non-GH-axis profile
- Weight reduction as monotherapy
- Additive effect with GLP-1 agonists
- Appetite and satiety modulation
- Weight reduction
- Glycemic control
- Cardiovascular outcomes
- Weight reduction
- Glycemic control
- Hepatic fat reduction
AOD-9604 is a synthetic 16-amino-acid peptide corresponding to the C-terminal 177-191 fragment of human growth hormone, modified with an N-terminal tyrosine. It was originally developed by Metabolic …
Cagrilintide is an investigational long-acting amylin analog engineered for once-weekly dosing. Amylin is co-secreted with insulin by pancreatic beta cells and acts on hypothalamic amylin receptors t…
Liraglutide is a daily-injected GLP-1 receptor agonist with ~97% homology to native human GLP-1 and a C16 fatty-acid side chain that enables albumin binding and extends half-life to ~13 hours. It enh…
Mazdutide is an investigational once-weekly dual agonist of the GLP-1 and glucagon receptors, structurally based on the mammalian peptide oxyntomodulin. GLP-1 activity drives appetite suppression, sl…
- Injection-site reactions (when administered subcutaneously)
- Headache reported in some trial participants
- Generally well-tolerated profile in Phase 2 human trials
- Gastrointestinal: nausea, vomiting, diarrhea (generally milder than GLP-1 class)
- Injection-site reactions
- Decreased appetite and early satiety
- Gastrointestinal: nausea, vomiting, diarrhea, constipation (titration-related)
- Injection-site reactions
- Hypoglycemia risk when combined with insulin or sulfonylureas
- Gastrointestinal: nausea, diarrhea, decreased appetite (titration-related)
- Injection-site reactions
- Transient heart rate elevation
- Pregnancy and lactation
- Active malignancy
- Pediatric use
- Pregnancy and lactation
- History of pancreatitis
- Severe gastroparesis
- Personal or family history of medullary thyroid carcinoma
- Multiple Endocrine Neoplasia syndrome type 2
- Pregnancy
- Personal or family history of medullary thyroid carcinoma
- Multiple Endocrine Neoplasia syndrome type 2
- Pregnancy and lactation
Think of it as
Think of it as a fat-burning assistant without the drama of full HGH.Best for
- Fitness enthusiasts looking to target stubborn fat areas
- People curious about alternatives to traditional HGH
- Those interested in managing weight with minimal side effects
Probably not for you if…
- Individuals expecting dramatic weight loss results
- People looking for a growth hormone replacement
- Anyone wary of peptides without extensive human trial success
Key benefits
- Lipolytic signaling (preclinical)
- Cartilage and joint research
- Non-GH-axis profile
Mechanism of action
AOD-9604 is a synthetic 16-amino-acid peptide corresponding to the C-terminal 177-191 fragment of human growth hormone, modified with an N-terminal tyrosine. It was originally developed by Metabolic …
Typical protocol
Reported side effects
- Injection-site reactions (when administered subcutaneously)
- Headache reported in some trial participants
- Generally well-tolerated profile in Phase 2 human trials
Contraindications
- Pregnancy and lactation
- Active malignancy
- Pediatric use
Stacks well with
Best $/mg
Think of it as
Think of it as a hunger-taming sidekick.Best for
- People looking to manage their weight more effectively.
- Those who struggle with feeling full after meals.
- Individuals interested in cutting-edge weight management options.
- Biohackers curious about new appetite-regulating peptides.
Probably not for you if…
- Anyone uncomfortable with investigational compounds.
- People seeking a quick fix without lifestyle changes.
- Individuals who prefer tried-and-true methods over new research.
Key benefits
- Weight reduction as monotherapy
- Additive effect with GLP-1 agonists
- Appetite and satiety modulation
Mechanism of action
Cagrilintide is an investigational long-acting amylin analog engineered for once-weekly dosing. Amylin is co-secreted with insulin by pancreatic beta cells and acts on hypothalamic amylin receptors t…
Typical protocol
Reported side effects
- Gastrointestinal: nausea, vomiting, diarrhea (generally milder than GLP-1 class)
- Injection-site reactions
- Decreased appetite and early satiety
Contraindications
- Pregnancy and lactation
- History of pancreatitis
- Severe gastroparesis
Stacks well with
Best $/mg
Think of it as
Think of it as a body double for appetite control.Best for
- People struggling with weight management who want to feel less hungry.
- Those managing type 2 diabetes looking for better blood sugar control.
- Individuals at risk of heart issues who need an additional protective measure.
Probably not for you if…
- Anyone uncomfortable with daily injections.
- People looking for an over-the-counter solution.
- Those who aren't managing weight or blood sugar issues.
Key benefits
- Weight reduction
- Glycemic control
- Cardiovascular outcomes
Mechanism of action
Liraglutide is a daily-injected GLP-1 receptor agonist with ~97% homology to native human GLP-1 and a C16 fatty-acid side chain that enables albumin binding and extends half-life to ~13 hours. It enh…
Typical protocol
Reported side effects
- Gastrointestinal: nausea, vomiting, diarrhea, constipation (titration-related)
- Injection-site reactions
- Hypoglycemia risk when combined with insulin or sulfonylureas
Contraindications
- Personal or family history of medullary thyroid carcinoma
- Multiple Endocrine Neoplasia syndrome type 2
- Pregnancy
Stacks well with
Best $/mg
Think of it as
Think of it as a metabolic multitasker.Best for
- People looking to lose weight when other methods haven't worked.
- Those managing type 2 diabetes and seeking better blood sugar control.
- Individuals curious about cutting-edge metabolic health strategies.
Probably not for you if…
- Anyone uncomfortable with investigational treatments or needles.
- Individuals not struggling with weight or metabolic health issues.
- Those looking for quick fixes without lifestyle changes.
Key benefits
- Weight reduction
- Glycemic control
- Hepatic fat reduction
Mechanism of action
Mazdutide is an investigational once-weekly dual agonist of the GLP-1 and glucagon receptors, structurally based on the mammalian peptide oxyntomodulin. GLP-1 activity drives appetite suppression, sl…
Typical protocol
Reported side effects
- Gastrointestinal: nausea, diarrhea, decreased appetite (titration-related)
- Injection-site reactions
- Transient heart rate elevation
Contraindications
- Personal or family history of medullary thyroid carcinoma
- Multiple Endocrine Neoplasia syndrome type 2
- Pregnancy and lactation
Stacks well with
Best $/mg
For research purposes only. Not medical advice.