CJC-1295 with DAC
CJC-1295 DAC · Drug Affinity Complex GRF · DAC:GRF
Think of it as a slow-release booster for your body's growth signals.
CJC-1295 with DAC is like a long-lasting release button for your body's natural growth signals. Normally, these signals come in short bursts, but this compound keeps the growth-promoting effects going for days. It's like having a steady stream of growth signals rather than quick, fleeting messages.
This means that with CJC-1295 with DAC, you don't need to worry about frequent injections. Just one or two times a week, and you're set. It's a bit like switching from a daily task to a weekly one, simplifying your routine if you're tracking growth over a longer period.
Who it's for
- Athletes looking for steady support in muscle growth and recovery
- Busy professionals who prefer less frequent injection schedules
- Biohackers interested in exploring long-term effects of growth hormone elevation
Probably not for you if…
- Those who prefer natural, non-synthetic interventions
- People uncomfortable with any form of injection
- Individuals not interested in manipulating growth hormone levels
Editorial summary for research context · Not medical advice
Mechanism of Action
CJC-1295 with DAC is a modified GHRH(1-29) analog covalently bound to a Drug Affinity Complex (maleimidopropionic acid) that attaches irreversibly to circulating serum albumin. This extends the half-life from minutes to roughly 6-8 days, producing sustained elevation of baseline GH and IGF-1 ('GH bleed') rather than discrete pulses. The compound retains GHRH-receptor agonism on pituitary somatotrophs but disrupts native pulsatility, a trade-off that is debated in research circles.
Researched Benefits
Sustained IGF-1 elevation
Phase 1 clinical work showed dose-dependent increases in mean plasma GH and IGF-1 persisting beyond one week after single subcutaneous administration.
- [Teichman et al. 2006]
Reduced injection frequency
Long albumin-bound half-life allows 1-2x weekly dosing in research protocols versus multiple daily injections for short-acting analogs.
Convenience for long-cycle research
Steady-state pharmacology simplifies IGF-1 tracking in longitudinal studies.
Research Protocols
The following dosing ranges have appeared in published research protocols. Presented for informational purposes only, not a recommendation for human use.
Weekly research protocol
- Dosage
- 2000 mcg
- Frequency
- once weekly
- Timing
- any time
- Cycle
- 8 weeks
Research protocols have used 1-2mg subcutaneous weekly. Some split the weekly dose into 2 injections (twice weekly) for smoother IGF-1 curves.
Reported Side Effects
- Water retention and mild edema, especially in first weeks
- Numbness or tingling in extremities (paresthesia)
- Headache and flushing post-injection
- Injection-site induration
- Potential for insulin sensitivity reduction at sustained elevated IGF-1
Contraindications
- Active malignancy
- Pregnancy and lactation
- Untreated sleep apnea
- Diabetic retinopathy or uncontrolled diabetes
Stacking Partners
Peptides commonly paired with CJC-1295 with DAC in published research and protocol write-ups.
Vendor Pricing
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Gear + Companions
Reconstitution supplies and research-backed supplement companions for CJC-1295 with DAC. Editorial picks only, we earn a commission through Amazon on the click, no sponsorship.
Gear you'll need
· Reconstitution + storage essentialsBacteriostatic Water 30mL (0.9% Benzyl Alcohol)
Empower Pharmacy / generic medical supply
Reconstitutes every lyophilized peptide. 28-day viability refrigerated.
Insulin Syringes 31G × 5/16" × 0.5mL (100 count)
EasyTouch
31G × 0.5mL insulin syringes — the default size for sub-0.25mL peptide doses.
Alcohol Prep Pads (Sterile, 200 count)
Dynarex
Sterile 70% IPA prep pads — one per vial stopper + one per injection site.
1-Quart Sharps Disposal Container
BD / Becton Dickinson
FDA-cleared sharps container — pharmacies won't accept improvised disposal.
Stacks well with
· Supplement companions, independent evidence, not sponsoredCreatine Monohydrate Powder 1kg
BulkSupplements
Creatine + GH-axis peptides increase lean-mass signaling via different pathways (IGF-1 + phosphocreatine replenishment). Most-studied stack in the literature.
Whey Protein Isolate 5 lb (Grass-Fed, Unflavored)
NAKED Nutrition
Growth-hormone-axis research is substrate-limited — without adequate protein intake the signaling can't translate to tissue.
As an Amazon Associate we earn from qualifying purchases · Disclosed per FTC guidelines
Top Videos
Curated from YouTube, refreshed weekly. Stacked doesn't host or endorse external content.
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Research Papers
Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults
Teichman SL, et al. · Journal of Clinical Endocrinology & Metabolism · 2006
PubMed 16352683 →
Frequently Asked
- What is CJC-1295 with DAC?
- CJC-1295 with DAC is a growth hormone studied in laboratory research. This profile covers its researched mechanism of action, study context, reported side-effect profile, and current vendor pricing. For research purposes only; not medical advice.
- Is CJC-1295 with DAC legal to buy?
- CJC-1295 with DAC is sold strictly for laboratory and research use and is not approved by the FDA for human consumption. Legal status and import rules vary by country and are the buyer's responsibility.
- How much does CJC-1295 with DAC cost?
- Compare live $/mg, total price, stock, and each vendor's Stacked Score for CJC-1295 with DAC on its price page. Stacked does not sell peptides; it links out to vetted research vendors.